PureBMC® is SupraPhysiologic BMC

Galvanizing the power of progenitor stem cells

PurePRP® and PureBMC® Supraphysiologic are currently not available for sale.  Projected availability is 2018

PureBMC® is now processed in a single GenesisCS Concentrating Device, producing supraphysiologic levels of progenitor stem cells consisting of hematopoietic stem cells, mesenchymal stem cells and total nucleated cells. The complexity of processing has been eliminated and the power of the PureBMC® biologic has been amplified. PureBMC® currently leads all point of care bone marrow concentrating systems in performance outcomes, and now go further with supraphysiologic procurement and quiescent cell collection, now achieved with the ASPIRE™ Bone Marrow Harvesting System.

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A purified progenitor biologic

Derived from parenchymal red bone marrow

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PureBMC® is now processed in a single Concentrating Device, producing supraphysiologic levels of progenitor stem cells consisting of hematopoietic stem cells, mesenchymal stem cells and total nucleated cells.  The complexity of processing has been eliminated and the power of the PureBMC® biologic has been amplified.  PureBMC® currently leads all point of care bone marrow concentrating systems in performance outcomes, and now go further with supraphysiologic procurement and quiescent cell collection, now achieved with the ASPIRE™ Bone Marrow Harvesting System.


 

PureBMC® is making a real difference

Features that truly improve outcomes

Extracellular hemoglobin is known to trigger specific pathologies associated with adverse clinical outcomes. PureBMC® collects and processes a pure sample of bone marrow with minimal hemolysis by virtue of its unique collection and processing technique.

Material mediated coagulation studies show that there is no statistical significant difference between the clot time of plasma and the PureBMC® concentrating device. This allows bone marrow to processed without heparin, ultimately preserving functionality of stem cells, platelets and growth factors.

PureBMC® has a progenitor cell viability of 97%, partially due to its gentle processing technique and quiescent aspiration attained with the ASPIRE™ bone marrow needle. This is the highest independently rated cell viability of any point of care bone marrow concentrating system.

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LESS TISSUE ACTIVATION

LESS CLOTTING

LESS FREE HEMOGLOBIN

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 PureBMC®

Independent Performance Evaluation

2017

 

PureBMC® volume (7.5mL)

 
CD34+ yield%
88%
CFU-f (MSC) yield % 88%
TNC yield % 80%
CD34+ concentration x baseline
7.3
CFU-f (MSC) concentration x baseline

7.4

TNC concentration x baseline
6.4
Platelet concentration x baseline
6.4
PDGF AB concentration x baseline 4.4
Call customer support for more information on data results

 

Biology of PureBMC® Regenerative Power

 

Hematopoietic Stem Cells

Hematopoietic stem cells (HSCs) has the ability to self-renew and to replenish all blood cell types (multipotency).  HSCs can replenish monocytes, macrophages, erythrocytes, megakaryocytes, platelets, neutrophils, basophils, eosinophils, dendritic cells and lymphoid lineage cells.  These cell types are crucial for the regenerative processes needed for active tissue repair.  Hematopoietic stem cells are produced in the pelvic, femur and sternal bone marrow and possess long-term and short-term regenerative capacities.

 

Mesenchymal Stem Cells

Mesenchymal stem cells (MSC) are multipotent stromal cells that can differentiate into a variety of cell types to include cartilage, bone and adipose tissue.  Mesenchymal stem cells are found in very small quantities in bone marrow aspirate, however, viable mesenchymal stem cells has powerful proliferative capabilities allowing it to be an effective biologic for regenerative therapies.

 

Total Nucleated Cells

Total nucleated cell count by any method is a count of cells with nuclei. In order to properly represent the TNC cell count a correction calculation that removes nucleated red blood cells (nRBCs) is performed. Total nucleated cells are a gross indicator of the quality of the bone marrow concentrate product.

 


 

Give us a Call

239-481-7725

Send us a message

support@emcyte.com

Visit our location

Fort Myers, FL 33916